Hormone Replacement Therapy Options
Oral hormone therapy is the most traditional and widely researched method of delivering estrogen, progesterone, or combined hormones. Swallowed daily, these tablets pass through the digestive system and are processed by the liver before entering the bloodstream. Because they have decades of clinical data backing them up, oral options are highly accessible and easy to use.
Oral hormone treatments are typically taken once a day, with or without food, at the same time each day to maintain steady baseline hormone levels.
Pills are generally best suited for healthy individuals under the age of 60 who are within 10 years of menopause onset and do not have pre-existing liver issues, high triglycerides, or significant blood clot risk factors.
Because oral hormones must be processed by the liver—a process called "first-pass metabolism"—they can slightly increase the risk of blood clots compared to topical options. They may also increase sex hormone-binding globulin (SHBG), which can sometimes lower active testosterone levels and impact libido.

Transdermal patches are small, adhesive squares applied directly to the skin (usually on the lower abdomen or buttocks) that release a steady, continuous dose of estrogen or combined hormones directly into the bloodstream. By bypassing the digestive tract and liver entirely, patches provide highly stable hormone levels throughout the day and night without the daily "peak and valley" fluctuations often experienced with oral pills.
Depending on the specific brand prescribed, patches are designed to be changed either once a week or twice a week.
Because transdermal delivery bypasses the liver, clinical data shows it does not increase the risk of blood clots or stroke the way oral estrogen can. This makes patches a preferred option for individuals with higher cardiovascular risk markers, obesity, or a history of migraines.
Yes. Modern medical adhesives are designed to withstand regular water exposure, sweat, and movement. However, it is important to avoid applying moisturizers, oils, or creams to the skin immediately before applying a new patch, as this can prevent proper adhesion.

Topical gels and transdermal sprays are frictionless, invisible alternatives to skin patches. Applied once daily to clean, dry skin—typically on the arms, shoulders, or inner thighs—these fast-absorbing formulas dry within minutes and deliver hormones directly through the skin barrier into the bloodstream. Like patches, they offer the safety benefits of bypassing liver metabolism while allowing healthcare providers to easily fine-tune dosages in small, incremental steps.
Most gels and sprays dry within two to five minutes. However, patients should wait at least one hour before bathing, swimming, or applying sunscreen to ensure the medication has fully absorbed.
Yes. To prevent accidental transfer to children, partners, or pets, you should cover the application site with clothing once dry and thoroughly wash your hands with soap and water immediately after application.
Yes. If you use a topical estrogen gel or spray and still have a uterus, you must also take a progestogen (such as an oral progesterone capsule or an intrauterine device) to protect the uterine lining from overgrowth.

Local vaginal hormone treatments are targeted therapies designed specifically to treat genitourinary symptoms of menopause, such as vaginal dryness, burning, and painful intercourse. Available as creams, dissolvable tablets, or flexible rings, these products deliver ultra-low doses of estrogen directly to the vaginal tissue. Because the hormones act locally, only a microscopic amount enters the rest of the body, offering a highly localized effect with an exceptional safety profile.
No. Because local vaginal treatments have minimal systemic absorption, they are highly effective for vaginal discomfort and urinary symptoms, but they do not provide enough systemic hormone levels to treat hot flashes, night sweats, or bone density loss.
Generally, no. Because the amount of estrogen absorbed into the bloodstream is so low, it does not typically cause overgrowth of the uterine lining, meaning a balancing progesterone treatment is rarely required for local therapy alone.
Vaginal creams and tablets are typically used daily for the first two weeks to rebuild the tissue, followed by a maintenance schedule of just two to three times a week. Vaginal rings are inserted once and left in place to release consistent local doses for up to 90 days.

Troches are small, lozenge-like tablets used in some forms of hormone replacement therapy (HRT) that dissolve slowly in the mouth, allowing hormones to be absorbed through the oral mucosa. This method can help bypass parts of the digestive system and liver metabolism, which may improve hormone availability for some patients. Troches are often compounded by specialized pharmacies, meaning they can be customized in dosage and combination (such as estrogen, progesterone, or testosterone) to fit individual needs. Because they are tailored and not mass-produced, consistency and proper use are especially important.
You place the troche between your cheek and gum (or under the tongue) and let it dissolve slowly over 15–30 minutes without chewing or swallowing it whole.
They can be beneficial for people who want customized dosing or to avoid first-pass liver metabolism, but they aren’t necessarily “better." The right option depends on your body, symptoms, and doctor’s guidance.
Yes. Because they’re compounded, quality and absorption can vary. They also require consistent use technique, and some people find the taste or the time it takes to dissolve inconvenient.

Hot Flashes
Sleep problems
Depressive mood
Anxiety
Physical and Mental Exhaustion
Sexual problems
Low libido
Excessive sweating
Poor sleep
Anxiety or nervousness
Low energy and
Irritability
Decreased ability to perform sexually
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No two bodies are identical, which means your hormone replacement therapy shouldn’t be either. We reject the "one-size-fits-all" approach to wellness, choosing instead to build a highly customized treatment plan tailored explicitly to your unique biochemistry, symptoms, and lifestyle goals. By utilizing comprehensive diagnostic testing alongside your personal health history, we identify exactly what your body needs to thrive. Whether your optimal path involves targeted topical gels, convenient weekly patches, or local therapies, we will carefully craft and continuously fine-tune a regimen that safely restores your balance and helps you feel like yourself again.

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